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Bioactivity:
BIBF0775 is a selective TGF_ type I receptor (Alk5) inhibitor (IC50: 34 nM).
CAS nr:
334951-90-5
Purity:
98%
Molecular Weight:
494,64
SMILES:
CCN(C)C(=O)c1ccc2c(NC(=O)\C2=C(/Nc2ccc(CN3CCCCC3)cc2)c2ccccc2)c1
Formula:
C31H34N4O2
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis,Stem Cells
Target:
ALK,ALK,TGF-beta/Smad