Bioactivity:

N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFR_, and KIT inhibitor.

CAS nr:

1261432-05-6

Purity:

98%

Molecular Weight:

406,88

SMILES:

O=C1C(C2=CC(F)=CC=C2N1)=CC(NC(C)=C3C(NCCNCC)=O)=C3C.Cl

Formula:

C20H24ClFN4O2

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR,VEGFR,VEGFR,c-Kit