Bioactivity:

AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.

CAS nr:

1009298-09-2

Purity:

98%

Molecular Weight:

465,54

SMILES:

COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C

Formula:

C25H31N5O4

Pathway:

PI3K/Akt/mTOR signaling,Autophagy,Apoptosis

Target:

mTOR,Autophagy,Apoptosis