Bioactivity:

JNJ525 is an inhibitor of TNF_. JNJ525 inhibits protein function via an aggregation-based mechanism. JNJ525 prevents the formation of TNF_ complexes with TNFR1 and TNFR2, the apparent IC50 values for the inhibition of complex formation are 1.2 ﾱ 0.2 _M an

CAS nr:

T27687

Purity:

98%

Molecular Weight:

514,64

SMILES:

NC1=NC=CC(N(CC2=CC=CC=C2)C(C=CC=C3)=C3C4=CC=CC(C5=CN=C(N6CCNCC6)N=C5)=C4)=N1

Formula:

C31H30N8

Pathway:

Target: