Bioactivity:

SB 399885 hydrochloride is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81 and 9.02 for human recombinant, native rat, and native human SR-6 recept

CAS nr:

402713-80-8

Purity:

98%

Molecular Weight:

482,8

SMILES:

O=S(C1=CC=C(OC)C(N2CCNCC2)=C1)(NC3=CC(Cl)=CC(Cl)=C3OC)=O.[H]Cl

Formula:

C18H22Cl3N3O4S

Pathway:

GPCR/G Protein,Neuroscience

Target:

5-HT Receptor,5-HT Receptor