Bioactivity:

Taltirelin is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1].

CAS nr:

103300-74-9

Purity:

98%

Molecular Weight:

405,41

SMILES:

CN1C(=O)C[C@H](NC1=O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(N)=O

Formula:

C17H23N7O5

Pathway:

Endocrinology/Hormones

Target:

Thyroid hormone receptor(THR)