Bioactivity:

E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)

CAS nr:

113559-13-0

Purity:

98%

Molecular Weight:

474,44

SMILES:

Cl.Cl.Cc1cccc(CCN2CCC(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)n1

Formula:

C21H29Cl2N3O3S

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling,Membrane transporter/Ion channel

Target:

EGFR,EGFR,EGFR,Potassium Channel