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Bioactivity:
R428 is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.
CAS nr:
1037624-75-1
Purity:
98%
Molecular Weight:
506,64
SMILES:
Nc1nc(Nc2ccc3CC[C@@H](CCc3c2)N2CCCC2)nn1-c1cc2CCCc3ccccc3-c2nn1
Formula:
C30H34N8
Pathway:
Tyrosine Kinase/Adaptors
Target:
TAM Receptor