Bioactivity:

Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(

CAS nr:

277751-61-8

Purity:

98%

Molecular Weight:

618,84

SMILES:

CC1(C)CC[C@@]2(CC[C@]3(COC(=O)\C=C\c4ccc(O)cc4)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O

Formula:

C39H54O6

Pathway:

Proteases/Proteasome,Apoptosis,PI3K/Akt/mTOR signaling,MAPK,Apoptosis,Microbiology/Virology,Apoptosis

Target:

Caspase,Caspase,PI3K,MEK,BCL,Antifection,p53