Bioactivity:

CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor with strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM).

CAS nr:

1353224-53-9

Purity:

98%

Molecular Weight:

321,37

SMILES:

OC1=CC=C(C2=NC3=CC=CC=C3C(OC4CCCC4)=C2)C=C1O

Formula:

C20H19NO3

Pathway:

Metabolism,Proteases/Proteasome

Target:

Acetyl-CoA Carboxylase,Acetyl-CoA Carboxylase