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Bioactivity:
NIK SMI1 is an effective and selective NF-_B inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23ﾱ0.17 nM).
CAS nr:
1660114-31-7
Purity:
98%
Molecular Weight:
365,38
SMILES:
O=C(N)C1=NC(C2=CC=CC(C#C[C@@]3(O)C(N(C)CC3)=O)=C2)=CC(OC)=C1
Formula:
C20H19N3O4
Pathway:
NF-_b
Target:
NF-_B