Bioactivity:

BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: 5.4 and 6.0 nM).

CAS nr:

1391107-54-2

Purity:

98%

Molecular Weight:

1065,68

SMILES:

O=C(C1=C(C)N(CC)C(C2=CC=C(Cl)C=C2)=C1C3=CC=CC(N4CCN(C5=CC=C(NS(=O)(C6=CC=C(N[C@H](CCN7CCC(O)CC7)CSC8=CC=CC=C8)C(S(=O)(C(F)(F)F)=O)=C6)=O)C=C5)CC4)=C3)O

Formula:

C52H56ClF3N6O7S3

Pathway:

Apoptosis

Target:

BCL