Bioactivity:

JHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively.�And EC50 values are 5 nM and 0.5 nM for hM3Dq

CAS nr:

2369979-67-7

Purity:

98%

Molecular Weight:

358,85

SMILES:

FC1=C2C(NC3=CC=C(Cl)C=C3N=C2N4CCN(CC)CC4)=CC=C1

Formula:

C19H20ClFN4

Pathway:

Neuroscience

Target:

AChR