Bioactivity:

G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.

CAS nr:

1457983-28-6

Purity:

98%

Molecular Weight:

521,41

SMILES:

CN1CCC(CC1)NC1=NC2=C(C(=O)NC=C2Br)C(NC2=CC=C(OC3=CC=CC=C3)C=C2)=N1

Formula:

C25H25BrN6O2

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Apoptosis,Tyrosine Kinase/Adaptors,Chromatin/Epigenetic,Cell Cycle/Checkpoint,Apoptosis

Target:

FLT,FLT,c-RET,c-RET,TAM Receptor,Aurora Kinase,Aurora Kinase,Apoptosis