Bioactivity:

GSK-626616 is a potent and orally bioavailable DYRK3 inhibitor (IC50: 0.7 nM). It inhibits other members of the DYRK family with similar potency. GSK-626616 is a potential therapy for the treatment of anemia.

CAS nr:

1025821-33-3

Purity:

98%

Molecular Weight:

401,27

SMILES:

O=C1N=C(NC2=C(Cl)C=CC=C2Cl)S/C1=C\C3=CC=C4N=CC=NC4=C3

Formula:

C18H10Cl2N4OS

Pathway:

Tyrosine Kinase/Adaptors,Cell Cycle/Checkpoint

Target:

DYRK,DYRK