S49076 HCl T3512
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo. In cell models, S49076 inhibited the proliferation of MET- an
CAS nr:
1265966-31-1
Purity:
98%
Molecular Weight:
439,85
SMILES:
C1COCCN1Cc1c[nH]c(c1)/C=C\1/c2c(ccc(c2)CN2C(=O)CSC2=O)NC1=O.Cl
Formula:
C22H18ClN3O5
Pathway:
Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors
Target:
TAM Receptor,FGFR,FGFR,c-Met/HGFR
