Bioactivity:

Cilengitide is a potent integrin inhibitor for _v_3 receptor and _v_5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.

CAS nr:

199807-35-7

Purity:

98%

Molecular Weight:

702,68

SMILES:

OC(=O)C(F)(F)F.CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

Formula:

C29H41F3N8O9

Pathway:

Cytoskeletal Signaling,Autophagy

Target:

Integrin,Autophagy