Bioactivity:

GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools.�GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1

CAS nr:

2133017-36-2

Purity:

98%

Molecular Weight:

373,35

SMILES:

O=C(C1=C(C)C(C(C(NCC#C)=O)=O)=C(C)N1C)NC2=CC=C(F)C(F)=C2

Formula:

C19H17F2N3O3

Pathway:

Microbiology/Virology

Target:

HBV