Bioactivity:

LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.

CAS nr:

154446-98-7

Purity:

98%

Molecular Weight:

433,42

SMILES:

O=C1C2=C(NCC(CCC(O3)=CC=C3C(N[C@@H](CCC(O)=O)C(O)=O)=O)C2)N=C(N)N1

Formula:

C19H23N5O7

Pathway:

DNA Damage/DNA Repair,Metabolism,Cell Cycle/Checkpoint

Target:

DHFR,DHFR,DHFR