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Bioactivity:
PF-06459988 is an irreversible T790M-Containing EGFR Mutants inhibitor.
CAS nr:
1428774-45-1
Purity:
98%
Molecular Weight:
431,88
SMILES:
Cn1ncc(Nc2nc(OC[C@@H](CN(C3)C(C=C)=O)[C@H]3OC)c(c(Cl)c[nH]3)c3n2)c1
Formula:
C19H22ClN7O3
Pathway:
JAK/STAT signaling,Tyrosine Kinase/Adaptors,Angiogenesis
Target:
EGFR,EGFR,EGFR