Bioactivity:

TrkA-IN-1 is a potent and selective inhibitor of Tropomyosin-related kinase A (TrkA) (IC50: 99 nM in a cell-based assay) with analgesic activity.

CAS nr:

1680179-43-4

Purity:

98%

Molecular Weight:

392,45

SMILES:

O=C(NC1=CN=C(C)N=C1C2=CC=CC=C2)NC3C4=C(C5=C3C=CC=C5)C=CC=C4

Formula:

C25H20N4O

Pathway:

Tyrosine Kinase/Adaptors

Target:

Trk receptor