Bioactivity:

W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophi

CAS nr:

405098-33-1

Purity:

98%

Molecular Weight:

493,08

SMILES:

O=C(C1CCCC2=C1C=C(OC)C=C2)N(CC3=CC=C(N(C)C)C=C3)C4=CC=C(C(C)C)C=C4.[H]Cl

Formula:

C30H37ClN2O2

Pathway:

Immunology/Inflammation

Target:

ROS