Bioactivity:

ML218 inhibits the burst activity in the subthalamic nucleus (STN) neurons. ML218 is an effective, selective, and orally active inhibitor of T-type Ca2+ channel (Cav3.1, Cav3.2, Cav3.3) (IC50s: 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively). ML218

CAS nr:

1346233-68-8

Purity:

98%

Molecular Weight:

369,33

SMILES:

O=C(NC[C@@H]1[C@@]2([H])CN(CCC(C)(C)C)C[C@@]12[H])C3=CC(Cl)=CC(Cl)=C3

Formula:

C19H26Cl2N2O

Pathway:

Microbiology/Virology,Immunology/Inflammation

Target:

CCR,CCR