Bioactivity:

Avitinib, also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potential antineoplastic activity. Upon oral administration, avitinib covalently binds to and inhibi

CAS nr:

1557267-42-1

Purity:

98%

Molecular Weight:

487,53

SMILES:

CN1CCN(CC1)C2=C(C=C(C=C2)NC3=NC4=C(C=CN4)C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)F

Formula:

C26H26FN7O2

Pathway:

JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells,Angiogenesis,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

JAK,JAK,JAK,JAK,BTK,BTK,EGFR,EGFR,EGFR