Bioactivity:

CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ﾱ 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with target

CAS nr:

2095432-28-1

Purity:

98%

Molecular Weight:

314,77

SMILES:

Cl.CC(C)C1=C(NC2=C(C=N[N]2C1=O)C#N)C3=CC=CC=C3

Formula:

C16H15ClN4O

Pathway:

Chromatin/Epigenetic

Target:

Histone Demethylase