TargetMol Chemicals

TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

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RGB-286638 free base T2378

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.

CAS nr:

784210-88-4

Purity:

98%

Molecular Weight:

545,63

SMILES:

COCCN1CCN(CC1)Cc1ccc(cc1)c1n[nH]c2c1C(=O)c1c2cccc1NC(=O)NN1CCOCC1

Formula:

C29H35N7O4

Pathway:

Cell Cycle/Checkpoint,Chromatin/Epigenetic,MAPK,Stem Cells,Angiogenesis,JAK/STAT signaling,Stem Cells,PI3K/Akt/mTOR signaling

Target:

CDK,JAK,MEK,JAK,JAK,JAK,GSK-3,GSK-3