Bioactivity:

BRD0476 is a suppressor of pancreatic _-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-_)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote _-cell survival. BRD0476 inhibits JAK-STAT

CAS nr:

1314958-91-2

Purity:

98%

Molecular Weight:

674,77

SMILES:

O=C(NC1=C2C=CC=CC2=CC=C1)NC3=C(O[C@@H](CN(S(=O)(C4=CC=C(OCCO5)C5=C4)=O)C)[C@H](C)CN([C@@H](C)CO)C6=O)C6=CC=C3

Formula:

C35H38N4O8S

Pathway:

Target: