Bioactivity:

LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo.�LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC50 of 24.5_�M and a Kd of 16_�M.

CAS nr:

T11896

Purity:

98%

Molecular Weight:

520,11

SMILES:

ClC1=CC2=NC=CC(/C=C/C3=CC=C(C(SCCC(O)=O)SCCC4=CC=CC=C4)C=C3)=C2C=C1

Formula:

C29H26ClNO2S2

Pathway:

Proteases/Proteasome

Target:

Cysteine Protease