NVP-TAE 226 T1918
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
NVP-TAE226 is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.
CAS nr:
761437-28-9
Purity:
98%
Molecular Weight:
468,94
SMILES:
CNC(=O)c1ccccc1Nc1nc(Nc2c(OC)cc(cc2)N2CCOCC2)ncc1Cl
Formula:
C23H25ClN6O3
Pathway:
Cytoskeletal Signaling,Apoptosis,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors
Target:
FAK,Apoptosis,FAK,FAK,IGF-1R,PYK2,c-Met/HGFR
