Bioactivity:

XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).

CAS nr:

1370888-71-3

Purity:

98%

Molecular Weight:

421,512

SMILES:

CCN(CC)S(=O)(=O)c1ccc(O)c(NC(=O)c2[nH]c(C)c(C(C)=O)c2CC)c1

Formula:

C20H27N3O5S

Pathway:

Chromatin/Epigenetic

Target:

Epigenetic Reader Domain