Bioactivity:

FGFR1/DDR2 inhibitor 1�is an inhibitor of discoindin domain receptor 2 (DDR2) and �fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.

CAS nr:

2308497-58-5

Purity:

98%

Molecular Weight:

501,5

SMILES:

CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=C(C=C3)C(=NN4)C5=CN(N=C5)C6CC6

Formula:

C28H22F3N5O

Pathway:

Tyrosine Kinase/Adaptors,Others,Tyrosine Kinase/Adaptors,Angiogenesis

Target:

Discoidin Domain Receptor (DDR),Others,FGFR,FGFR