Bioactivity:

ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)

CAS nr:

1434639-57-2

Purity:

98%

Molecular Weight:

568,64

SMILES:

COc1ccccc1[C@H](Cn1c2sc(-c3ncco3)c(C)c2c(=O)n(c1=O)C(C)(C)C(N)=O)OC1CCOCC1

Formula:

C28H32N4O7S

Pathway:

Metabolism,Proteases/Proteasome

Target:

Acetyl-CoA Carboxylase,Acetyl-CoA Carboxylase