Inauhzin T1887
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
CAS nr:
309271-94-1
Purity:
98%
Molecular Weight:
469,58
SMILES:
CCC(Sc1nc2c(nn1)c1ccccc1[nH]2)C(=O)N1c2ccccc2Sc2ccccc12
Formula:
C25H19N5OS2
Pathway:
DNA Damage/DNA Repair,Chromatin/Epigenetic
Target:
Sirtuin,Sirtuin
