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Bioactivity:
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met with a mean IC50 of 2.5 nM.
CAS nr:
917879-39-1
Purity:
98%
Molecular Weight:
495,55
SMILES:
Cn1cc(cn1)c1cnc2ccc3c(cc(cc3)NS(=O)(=O)N(C)C[C@@H]3COCCO3)c(=O)c2c1
Formula:
C24H25N5O5S
Pathway:
Tyrosine Kinase/Adaptors
Target:
c-Met/HGFR