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Bioactivity:
TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).
CAS nr:
1361951-15-6
Purity:
98%
Molecular Weight:
418,46
SMILES:
CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1
Formula:
C22H25F3N4O
Pathway:
JAK/STAT signaling,Chromatin/Epigenetic
Target:
Pim,Pim