Bioactivity:

3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 _M), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 _M). It suppresses glucose uptake, and decreases the intracellular concentration

CAS nr:

18550-98-6

Purity:

98%

Molecular Weight:

210,23

SMILES:

O=C(/C=C/c1cnccc1)c1ccncc1

Formula:

C13H10N2O

Pathway:

Metabolism,Autophagy

Target:

Glucokinase,Autophagy