Bioactivity:

4-Methylumbelliferyl-_-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of _-glucosidase and _-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel _-glucosidases, 4-MUG is used in assays to evaluate deficiency in _- glucocerebrosidase activity related to Gaucher disease.1,2,3Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.4

CAS nr:

18997-57-4

Purity:

Molecular Weight:

338,312

SMILES:

Cc1cc(=O)oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

Formula:

C16H18O8

Pathway:

Others

Target:

Others