Bioactivity:

Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blockin

CAS nr:

300815-04-7

Purity:

98%

Molecular Weight:

438,65

SMILES:

Cc1ncc(n1CCOC(=O)NC(Nc1ncccn1)C(Cl)(Cl)Cl)[N+]([O-])=O

Formula:

C13H14Cl3N7O4

Pathway:

Cell Cycle/Checkpoint

Target:

APC