Bioactivity:

CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 _M and it shows 37-fold more selective for S1P4-R than S1P5-R.

CAS nr:

1345858-76-5

Purity:

98%

Molecular Weight:

405,46

SMILES:

O=C1N(C)/C(S/C1=C\C2=C(C)N(C3=CC=C(F)C=C3F)C(C)=C2)=N/CCOC

Formula:

C20H21F2N3O2S

Pathway:

GPCR/G Protein,GPCR/G Protein

Target:

LPL Receptor,S1P Receptor