Bioactivity:

Rotundic acid, a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.

CAS nr:

20137-37-5

Purity:

98%

Molecular Weight:

488,7

SMILES:

C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@]1(C)O)C(O)=O

Formula:

C30H48O5

Pathway:

PI3K/Akt/mTOR signaling,Others,MAPK,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,Apoptosis

Target:

mTOR,Others,p38 MAPK,Akt,Akt,Apoptosis