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Bioactivity:
OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
CAS nr:
183321-86-0
Purity:
98%
Molecular Weight:
379,41
SMILES:
COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCO
Formula:
C21H21N3O4
Pathway:
Metabolism,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling
Target:
Drug Metabolite,EGFR,EGFR,EGFR