Bioactivity:

AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.

CAS nr:

1645286-75-4

Purity:

98%

Molecular Weight:

428,53

SMILES:

C[C@H]1CN(C[C@@H](C)N1)c1cc(C)c(cn1)-c1ccc(cc1)-c1nc2n(C)ccc2c(=O)[nH]1

Formula:

C25H28N6O

Pathway:

Stem Cells,Cytoskeletal Signaling,DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

Wnt/beta-catenin,Wnt/beta-catenin,PARP,PARP