Bioactivity:

Gypenoside XVII confers protection against A_25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/ARE/HO-1 and inactivation of GSK-3_ pathways.

CAS nr:

80321-69-3

Purity:

98%

Molecular Weight:

947,16

SMILES:

C\C(C)=C/CC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@@H]3CC[C@@]21C

Formula:

C48H82O18

Pathway:

Endocrinology/Hormones,Metabolism,Stem Cells,PI3K/Akt/mTOR signaling

Target:

Estrogen Receptor/ERR,Endogenous Metabolite,GSK-3,GSK-3