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A 83-01 T3031

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

A 83-01 is a selective inhibitor of TGF-_ type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 with IC50 values of 12 nM, 45 nM and 7.5 nM, respectively.

CAS nr:

909910-43-6

Purity:

98%

Molecular Weight:

421,52

SMILES:

Cc1cccc(c2c(cn(C(=S)Nc3ccccc3)n2)c2ccnc3ccccc23)n1

Formula:

C25H19N5S

Pathway:

Stem Cells,Tyrosine Kinase/Adaptors,Angiogenesis

Target:

TGF-beta/Smad,ALK,ALK