Bioactivity:

AG311 is an inhibitor of complex I and hypoxia-induced HIF-1_ stabilization. In vitro, AG311 induces rapid necrosis in numerous cancer cell lines. Within minutes, exposure to AG311 also results in mitochondrial depolarization, superoxide production, and i

CAS nr:

1126602-42-3

Purity:

98%

Molecular Weight:

321,4

SMILES:

NC1=NC(N)=C2C(NC3=C2C(SC4=CC=C(C)C=C4)=CC=C3)=N1

Formula:

C17H15N5S

Pathway:

Target: