Bioactivity:

TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFR_, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively).

CAS nr:

867334-05-2

Purity:

98%

Molecular Weight:

475,97

SMILES:

ClC1=CC=C(O)C=C1C2=CC(C)=C(N=C(NC(C=C3)=CC=C3OCCN4CCCC4)N=N5)C5=C2

Formula:

C26H26ClN5O2

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

VEGFR,VEGFR