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Bioactivity:
PF-6422899 irreversibly inhibits EGFR kinase activity by binding covalently to active-site cysteine residues in the ATP binding pocket of EGFR.
CAS nr:
1621002-23-0
Purity:
98%
Molecular Weight:
396,81
SMILES:
C=CC(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OCC#C)=O
Formula:
C20H14ClFN4O2
Pathway:
Target: