Bioactivity:

USP30 inhibitor 18 is a selective USP30 inhibitor with an IC50 of 0.02 _M. USP30 inhibitor 18 increases protein ubiquitination and accelerates mitophagy[1]. [1]. Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.

CAS nr:

2242582-40-5

Purity:

98%

Molecular Weight:

497,58

SMILES:

N/A

Formula:

C26H28FN3O4S

Pathway:

Ubiquitination,Cell Cycle/Checkpoint,DNA Damage/DNA Repair

Target:

DUB,DUB,DUB