Bioactivity:

ML230 is a selective ATP-binding cassette (ABC) transporter ABCG2 inhibitor. It 36-fold selective for ABCG2 over ABCB1 (EC50s: 0.13 _M and 4.65 _M, respectively).

CAS nr:

1776055-05-0

Purity:

98%

Molecular Weight:

439,47

SMILES:

O=C(C1=COC=C1)N2CCN(C3=CC(C4=CC=CO4)=NC5=CC(C6=CC=CC=C6)=NN53)CC2

Formula:

C25H21N5O3

Pathway:

Membrane transporter/Ion channel

Target:

CGRP Receptor