Bioactivity:

CGP52411 (DAPH) is a highly selective, orally active, and ATP-competitive EGFR inhibitor (IC50: 0.3 _M). It blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of _-amyloid (A_42) fibril aggregates

CAS nr:

145915-58-8

Purity:

98%

Molecular Weight:

329,35

SMILES:

O=C1NC(C2=C1C=C(NC3=CC=CC=C3)C(NC4=CC=CC=C4)=C2)=O

Formula:

C20H15N3O2

Pathway:

Others

Target:

Others